Pdf subungal glomus tumor a case report researchgate. A curative segmental tracheal resection with primary reconstruction was performed with no recurrence at 6year followup. The current case reported a 30yearold woman with dyspnea on exertion and hemoptysis, she had a glomus tumor which has large size, deep location and exhibits an infiltrative. A welldefined, intradermal, elastic, firm nodule of 1. Although some of our patients were evaluated following specific referral, many were not, and were diagnosed because we specifically asked about fingertip pain. Glomus tumor was also the name formerly and incorrectly used for a tumor now called a paraganglioma a glomus tumor also known as a solitary glomus tumor, solid glomus tumor, is a rare neoplasm arising from the glomus body and mainly found under the nail, on the fingertip or in the foot. The diagnosis of this disease is also a critical affair due to its. Gastric glomus tumor journal of surgical case reports. The pathologic diagnosis was glomus tumor of the penis. A local resection was performed at the time of surgery. Diagnosis, management, and complications of glomus tumors. The glomus apparatus or glomus body is a part of the dermal layer of the skin and is thought to aid in temperature regulation.
Symplastic glomus tumor a rare but distinct benign. Glomus tumor is a rare vascular neoplasm arising from a neuroarterial. Glomus tumors gts are rare, benign tumors arising from neuromyoarterial glomus bodies, accounting for less than 2% of soft tissue tumors, and a malignant transformation of this tumor with metastasis is possible but remains exceptional. Combination of glomus cells, smooth muscle cells and vasculature. Glomus tumors are unusual lesions, which can present a diagnostic enigma to an unaware rheumatologist. A 66yearold man presented with acute respiratory distress due to a tracheal tumor involving the posterior wall of the upper trachea, with nearly complete airway obstruction. Glomus vagale tumors, specifically, grow in the paraganglia located near the vagus nerve, an important cranial nerve which serves many functions including empowering the vocal cords and the muscles of swallo. Mar 22, 2010 gastric glomus tumors are rare mesenchymal tumors of the gastrointestinal tract. Herein we discuss a patient with a tracheal glomus tumor. Glomus tumor is a benign and vascular hamartoma that originates from the neuromyoarterial cells of the normal glomus apparatus in the. Glomus tympanicum tumor also known as paraganglioma or chemodectoma is the most benign tumor of temporal bone. Imaging is very useful for diagnosing tumors of the nail unit. Four were in glomus jugulare tumors and one was a carotid body tumor. Only 2 cases have been reported in the literature to date.
Most glomus tumors occur in the distal parts of the extremities. Pathologic and immunohistochemical findings following surgical resection were consistent with a gastric glomus tumor. The majority of glomus tumors occur in the dermis or subcutis of the extremities. Seventyfive per cent of these occur in the hand, and most are. Glomus tumors most commonly occur in the hand and specifically the subungual region of the distal phalanx. Abstract glomus tumor is a benign mesenchymal neoplasm comprising less than 2% of soft tissue tumors.
From our experience, we estimate that glomus tumors of the fingers may affect up to 5 % of the adult nf1 population. It could be a challenge for pathologists who have no experience with it because the tumor can show marked nuclear atypia and pleomorphism. Partial debulking of the tumor s endoluminal component, via rigid bronchoscopy and yttriumaluminumperovskite laser, allowed timely and effective airway restoration. Jul 16, 2019 glomus tumor is a benign tumor arising from the dermis layer of the skin beneath the nails of fingers and toes normally. J dermatitis, an open access journal volume issue 1 110 figure 1. Gastric glomus tumors ggts are rare mesenchymal tumors. A multidisciplinary approach to management lama sakr md, ramanathan palaniappan md, mariejose. High rates of morbidity, incomplete resection, and the aggressive behavior of these tumors are the main arguments for. The diagnosis and treatment of glomus tumor cleveland. Glomus tumors are not often encountered in the foot. Glomus tumor of the trachea the annals of thoracic surgery. The treatment of choice for glomus jugulare tumors is still controversial. Glomus tumor should be considered in the differential diagnosis of any acutely painful subcutaneous or subungual lesion.
Glomus tumor is a nonmalignant vascular tumor that does not commonly occurs to a person and should not be confused with paraganglioma. Apr 25, 2016 glomus vagale tumor is a type of paraganglioma, which is a tumor that develops in the paraganglia a group of cells that are found near nerve cell bunches called ganglia. While incomplete resection may result in recurrence, local recurrence is very uncommon. Glomus tumors classically present with a triad of symptoms.
Glomus vagale tumor genetic and rare diseases information. Histologically, the diagnosis of a subungual glomus tumor was made. Palliative therapy includes watchful observation or radiotherapy and curative treatment is surgical. Mesenchymal tumor composed of modified smooth muscle cells arising from the glomus body. The neuromyoarterial glomus is a cutaneous structure whose function is temperature regulation via arteriovenous shunting of blood. Glomus tumor of the hand is an uncommon cause of distal finger pain. Glomus tumor symptoms, pictures, causes, diagnosis. Typically, a glomus tumor of the finger presents with a triad of localized tenderness, severe paroxysmal pain out of proportion to size and sensitivity to cold. We describe a 73yearold man with a glomus tumor of the trachea who presented with cough, dyspnea, chest pain, and hemoptysis. Predominantly cutaneous, most common in subungual region of the finger but may occur anywhere.
Glomus tumor of uncertain malignant potential in upper extremity. Aug 26, 2009 the histological features and immunoprofile were consistent with the diagnosis of symplastic glomus tumor, a rare histological variant, which has been defined as a glomus tumor exhibiting marked nuclear atypia, in the absence of any other criteria for malignancy. They arise from the normal glomus apparatus, located in the subcutaneous tissue. Glomus tumor is usually a small, benign tumor and typically occurs in the dermis or subcutis or soft tissue of the extremities and rarely in the visceral locations. Glomus tumors are usually presented with late diagnosis and treatment. Glomus tumor simulating nerve root compression and raynauds. Consideration of gastric glomus tumors in the differential diagnosis may optimize the chance for a more accurate preoperative diagnosis and targeted surgical intervention. Nasopharyngeal extension of the glomus tympanicum is rare. Glomus tumors are rare, benign vascular neoplasms seen most often in the nail beds of the hands.
The glomus is a normal structure in the stratum reticulare corii and seldom is more than 1 mm. The glomus is a specialized anastomotic mechanism connecting a terminal arteriole with a primary venule. Oct 18, 2018 glomus tumor is a benign and vascular hamartoma that originates from the neuromyoarterial cells of the normal glomus apparatus in the reticular dermis. Typically, gt occurs in the hand and are relatively easily diagnosed following the classic triad of pain. This slow process may be caused due to the pain that only.
We report a rare case of a glomus tumor presenting as a painless lump in the upper lip. Article pdf available in journal of pakistan association of dermatologists 201. On the other hand, us is able to demonstrate the size, site, and shape of the tumor, even if the tumor is not palpable 5. However, glomus tumors of the fingers are underrecognized. The clinicopathologic features of this unusual neoplasm are discussed. The combination of clinical testing, us, and mri allows for early and accurate diagnosis of glomus tumors.
Its occurrence in the main bronchus is extremely rare. We describe a 72yearold patient who presented with episodes of melena and was subsequently investigated for a tumor of the antrum of the stomach. Oct 10, 2018 the histomorphological characteristics and positive expression of both actin and desmin can be used to positively identify a glomus tumor. Most patients with glomus tumor are women 30 to 50 years of age. We diagnosed the exact location and size of the subungual glomus tumor by preoperative imaging and completely removed it easily and safely.
Glomus tumors in nf1 are more common than previously suspected. Dutau md a 66yearold man presented with acute respiratory distress due to a tracheal tumor involving the posterior wall of the upper trachea, with nearly complete airway. Pdf glomus tumors are rare vascular tumors that are found most commonly in the hand. Glomus tumors are benign hamartomas that account for 1% to 5% of all softtissue tumors of the hand. Although these lesions can occur anywhere in the body, the subungual tissue of the hand represents the most common presentation site. A glomus tumor is an uncommon, predominantly benign, neoplastic lesion that primarily involves a thermoregulatory microvascular apparatus, the glomus body. Despite its high nuclear grade, a symplastic glomus tumor itself has a benign biologic behavior. It usually presents as a small, slightly raised, bluish or pinkishred, painful nodule of the fingertips and the pulp. Even if a tumor is small and not causing severe symptoms, it may need to be removed.
Diagnosis, management, and complications of glomus tumors of. Glomus tumors are benign vascular neoplasms that arise from specialized dermal arteriovenous anastomoses called glomus bodies. The most common location was the antrum, the mean age of patients was 49. Egyptian journal of plastic and reconstructive surgery 35. It is composed of cells resembling modified smooth. The glomus tumor is considered to be the most common of all tumors that involve the middle ear. In the gut, they are almost exclusively found in the stomach. Tumor of the glomus jugulare with extension into the middle ear nonchromaffin paraganglioma or carotidbodytype tumor. The differential for this tumor includes carcinoid tumors, paragangliomas, and hemangiomas, and. A glomus tumor is rare, usually benign, soft tissue neoplasm. Glomus tumor is a benign and vascular hamartoma that originates from the neuromyoarterial cells of the normal glomus apparatus in the reticular dermis. A patient with multiple regional glomus tumors involving the penis is reported. Extracutaneous glomus tumors are uncommon and rarely occur in the trachea.
Glomus tumors are encountered most frequently in the subungual region of digits, but can be found almost anywhere in the body 1. There have been only seven previous cases reported in the literature of glomus tumor in the colon, 3 of which were in the anorectal area. Most glomus tumors are usually solitary, small, normally less than 1 cm and redviolet. Pdf surgery of glomus jugulare tumors researchgate. Glomus tumor of uncertain malignant potential arising in the. Glomus tumor of the penis saito 2000 international. On pathology, glomus tumors are made up of glomus cells, blood vessels, and smooth muscle and are classified based on the predominant cell type. We report the fourth case of glomus tumor in the anorectum, and 7th in the colon. It is the result of tumor formation of the glomus body, which is a neuromyoarterial apparatus whose function is to regulate peripheral blood flow in the digits. Glomus tumor is a neoplasm, usually located in the skin or soft tissue, characterized clinically by paroxysmal pain. This report defines the glomus tumor and discusses the symptomatology of the tumor with respect to the various developmental courses it may follow. The basic causes are not clear to the experts and researchers. Magnetic resonance imaging mri is an excellent imaging modality in the detection of glomus tumour and also in delineating its anatomical. Here, we retrospectively analyzed the features of ggts from two institutions.
Although an ovarian glomus tumor is extremely rare, the authors believe that it should be. Recurrent and multiple digital glomus tumors ecronicon. Glomus tumor of the toe journal of the american podiatric. Digital glomus tumors have often passed undiagnosed because of a lack of familiarity with them. Glomus tumours gt, neoplasms of the glomus body comprise 4. Pdf the treatment of choice for glomus jugulare tumors is still controversial. When a glomus tumor is suspected in the breast, us is the first imaging technique preformed because patients usually are unable to tolerate compression because of severe pain 6. At imaging, glomus tumors typically manifest as an extremely painful, hypervascular wellmarginated superficial mass 6. The tumor arise from the glomus body which is a part of the skins dermis layer and is involved in the human bodys thermoregulation. When exposed to cold temperatures, the glomus body moves blood away from the skins surface to reduce heat loss. The only real treatment for a glomus jugulare tumor is surgery.
1280 452 1041 538 603 419 794 1061 624 1374 587 915 616 1090 1156 1092 270 676 548 325 884 941 1284 856 997 423 1482 486 386 5 1373 1244 296 848 666 1168 847 84